Prof. Dr. Mehmet Dinçer Bilgin
Prof. Dr. Mehmet Dinçer Bilgin is a physician-scientist and Professor of Biophysics at Aydın Adnan Menderes University Faculty of Medicine (Türkiye), where he has served as Head of the Department of Biophysics since 2001. His research focuses on the translational biomedical applications of light and ultrasound, with particular emphasis on noninvasive cancer diagnosis and therapy.
He received his MD from Ankara University and completed his PhD in Biophysics at the Illinois Institute of Technology (Chicago, USA; 1994–1999). His doctoral thesis, Biomedical Applications of Photosensitization, investigated the mechanisms of photodynamic therapy, including singlet oxygen generation, dose optimization, and membrane-level interactions of photosensitizers. During this period, he was a member of the photodynamic therapy team at the Wenske Laser Center, Ravenswood Hospital. He subsequently conducted postdoctoral research in Cellular Biophysics at Northwestern University Feinberg School of Medicine (Chicago, USA), where he further expanded his expertise in cancer biology and experimental biophysics.
Prof. Dr. Bilgin’s research integrates biophysics and clinical medicine to develop innovative therapeutic strategies, particularly photodynamic therapy, sonodynamic therapy, and combined sono-photodynamic therapy. His work has contributed to the understanding of cavitation-induced cytotoxicity, the mitochondrial unfolded protein response, and reactive oxygen species-mediated signaling in cancer cells, with applications in prostate, breast, and gastrointestinal malignancies. He has also conducted studies on tissue optics, laser–tissue interactions, reflectance spectroscopy, and the biomedical applications of non-ionizing radiation, electromagnetic fields, and therapeutic ultrasound.
He has authored over 60 peer-reviewed publications indexed in Web of Science (h-index: 15; ~960 citations as of 2026) and has delivered approximately 150 presentations at national and international scientific meetings. He has supervised nine MSc and twelve PhD theses and has contributed to more than 15 nationally funded research projects supported by TÜBİTAK and TÜSEB. His mentorship includes doctoral research on neural therapy combined with photobiomodulation in diabetic neuropathy (2025), neural therapy and electrical stimulation in an experimental colitis model (2023), and quercetin combined with low-level laser therapy in cisplatin-induced peripheral neuropathy models (2022).
In addition to biomedical research, Prof. Dr. Bilgin is actively engaged in Traditional and Complementary Medicine (GETAT), with a focus on the scientific and mechanistic evaluation of integrative therapies. His work encompasses acupuncture (including auricular, electroacupuncture, and laser acupuncture), pharmacopuncture, neural therapy, photobiomodulation, ozone therapy, and mesotherapy. He particularly investigates their effects on autonomic nervous system regulation, heart rate variability (HRV), inflammation, and tissue repair, aiming to establish evidence-based frameworks for integrative medicine. He is also involved in academic training, clinical applications, and interdisciplinary collaboration in this field.
He has contributed to recent academic volumes, including The Language of the Heart: Reading the Biophysical Rhythms of Life through HRV (2026) and The Enteric Nervous System: The Silent Brain of the Body and the Key to Health (2026), reflecting his interest in systems physiology/biophysics, neurogastroenterology, and biophysical regulation.
His interdisciplinary approach combines physics, biology, biophysics, and clinical medicine to advance mechanism-based, noninvasive therapeutic technologies.
ORCID: 0000-0003-0754-0854